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Synergies Isaac (updated 2025-03-12)

The BEST Ipecac Synergy Viewer Synergies 10 SlayXc2 [upl. by Lekcar]
Duration: 6:19
226.6K views | Aug 23, 2021
TOP 10 BRIMSTONE SYNERGIES Binding of Isaac Afterbirth [upl. by Keene478]
Duration: 10:15
878.2K views | Aug 20, 2017
Binding of Isaac Afterbirth Item guide Haemolacria [upl. by Engelhart]
Duration: 5:52
117.7K views | Oct 12, 2017
TAINTED TREASURES [upl. by Lietman]
Duration: 1:15
81.9K views | 3 months ago
DEMONIC SIGILS [upl. by Uyerta611]
Duration: 0:58
45.8K views | 2 months ago
BRIMSTONE ROCKET [upl. by Amann]
Duration: 0:59
35.7K views | 2 months ago
ISAAC TRANSFORMATIONS [upl. by Shulem]
Duration: 0:59
140.9K views | 3 months ago
DELIRIOUS TECH [upl. by Naik397]
Duration: 1:00
12K views | 2 weeks ago
VIEWER WILD SYNERGIES [upl. by Ultima]
Duration: 11:23
48.6K views | 5 months ago
quotNEWquot CHARACTER MEI [upl. by Saffren]
Duration: 0:59
17.3K views | 2 months ago
NEW SYNERGIES DR FETUS 3 [upl. by Occer]
Duration: 0:59
22.1K views | 1 month ago
22 NEW Custom Dr Fetus Synergies [upl. by Nesmat]
Duration: 8:52
180.2K views | Nov 22, 2022
12 NEW Custom Neptunus Synergies [upl. by Marcy670]
Duration: 8:05
73K views | May 2, 2023
15 NEW Custom Spirit Sword Synergies [upl. by Annaed]
Duration: 8:02
116.5K views | Nov 26, 2022
EPIC GIGA BOMB SYNERGIES 2 [upl. by Ahsitil]
Duration: 0:57
18K views | 2 months ago
I Got the PERFECT Synergy [upl. by Ysdnil]
Duration: 1:13:47
464 views | 1 month ago
The LUCKIEST Rig Ever [upl. by Cornew998]
Duration: 24:24
174.7K views | 8 months ago
The WORST Start In Isaac History [upl. by Egiedan378]
Duration: 23:47
134.6K views | 9 months ago
Best synergies isaac [upl. by Byram]
Duration: 0:58
4.6K views | 4 weeks ago
They Added NEW Flat Stone Synergies [upl. by Attennot267]
Duration: 17:07
159.5K views | Jun 15, 2023
Synergies from your comments Part 1 [upl. by Weywadt]
Duration: 0:39
14.3K views | 4 months ago
Frog Moment 🐸 [upl. by Kenleigh246]
Duration: 19:17
112.9K views | 9 months ago
These NEW Synergies Are INSANELY FUN [upl. by Auot]
Duration: 26:31
178.4K views | 8 months ago
These New Synergies Are INCREDIBLE [upl. by Margery609]
Duration: 23:24
201.2K views | Aug 2, 2023
Character Synergies Are in Coop Isaac [upl. by Ydennek]
Duration: 12:34
31.3K views | Nov 24, 2023
NEW SYNERGIES MOMS KNIFE 2 [upl. by Kcub]
Duration: 1:00
67K views | 1 month ago
SMARTEST BINDING OF ISAAC SYNERGIES [upl. by Pompea]
Duration: 1:00
661.5K views | 8 months ago
The Isaac Mod That BROKE My Mind [upl. by Guinevere]
Duration: 22:21
65.9K views | Mar 11, 2024
18 NEW Custom MOMS KNIFE Synergies [upl. by Moshell161]
Duration: 8:36
119.5K views | Dec 19, 2022
This Mod BUFFS All Bad Transformations [upl. by Negaem880]
Duration: 8:51
286.4K views | Apr 8, 2023





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